Table 2.
The Association Between Mental Health and Anticoagulation Control Stratified by Psychiatric Hospitalization History Among Experienced Warfarin Users with Mental Health Conditions (N = 28,216)
| Psychiatric hospitalization | Overall | ||||
|---|---|---|---|---|---|
| None | At least one | ||||
| N | Mean TTR | N | Mean TTR | TTR | |
| No mental health condition | 75,681 | 63.2 % | – | – | 63.2 % |
| Any mental health condition | 26,562 | 57.6 % | 1,654 | 50.5 %* | 57.1 %‡ |
| Diagnostic groups | |||||
| Anxiety disorders | 8,044 | 57.8 % | 73 | 54.4 % | 57.8 %‡ |
| Bipolar disorder | 2,102 | 54.0 % | 316 | 46.9 %* | 53.1 %‡ |
| Depression | 18,795 | 56.8 % | 780 | 50.0 %* | 56.5 %‡ |
| PTSD | 7,219 | 57.1 % | 329 | 51.5 %* | 56.8 %‡ |
| Schizophrenia | 847 | 55.1 % | 257 | 50.8 %† | 54.1 %‡ |
| Other psychotic disorders | 1,909 | 54.3 % | 86 | 48.2 %† | 54.0 %‡ |
MHC: Mental health condition; PTSD: post-traumatic stress disorder
TTR: Percent time in the therapeutic range
*p < 0.05 and †p < 0.001 (t-test) compared to those without psychiatric hospitalization in the same category
‡p < 0.001 (t-test) compared to those without mental health conditions