Table 3.
Kinase | SVM
|
MLP
|
K-NN
|
||||||
---|---|---|---|---|---|---|---|---|---|
B=10 | B=15 | B=20 | B=10 | B=15 | B=20 | B=10 | B=15 | B=20 | |
PKA | 66.25 | 65.43 | 63.44 | 55.67 | 60.06 | 56.85 | 59.25 | 59.72 | 56.94 |
PKB | 71.69 | 78.61 | 66.98 | 55.42 | 69.26 | 59.09 | 67.61 | 68.57 | 63.8 |
PKC | 68.85 | 61.72 | 60.76 | 64.84 | 57.88 | 54.7 | 61.33 | 61.09 | 55.36 |
MAPK | 61.24 | 67.67 | 62.02 | 57.52 | 58.72 | 58.67 | 57.41 | 60.91 | 61.45 |
GSK-3 | 67 | 73.16 | 66.5 | 59.5 | 56.41 | 58.12 | 68.75 | 66.25 | 71.25 |
CDK1 | 83.8 | 65.53 | 65.9 | 75.5 | 60.26 | 58.22 | 77.5 | 61 | 57 |
CK2 | 67.35 | 64.9 | 67.42 | 57.36 | 59.69 | 56.97 | 58 | 64.41 | 60.49 |
CAM KII | 78.2 | 71.2 | 73.6 | 61.98 | 61.58 | 56.788 | 74.25 | 60.39 | 68.31 |
SRC | 66.44 | 65.48 | 68.55 | 58.83 | 58.18 | 55.3 | 63.88 | 75 | 60 |
Note: Physicochemical properties of amino acids are used for sequence encoding.
Abbreviations: CAM KII, calmodulin-dependent protein kinase II; CDK1, cyclin-dependent kinase 1; CK2, casein kinase 2; GSK-3, glycogen synthase kinase 3; K-NN, K-nearest neighbor; MAPK, mitogen-activated protein kinase; MLP, multilayer perceptron; PKA, protein kinase A; PKB, protein kinase B; PKC, protein kinase C; SRC, tyrosin kinase SRC; SVM, support vector machine.