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. 2014 May 19;9(5):e97274. doi: 10.1371/journal.pone.0097274

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© 2014 Yang et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Mutation frequency comparison of AHC. Each dot represented one mutation, whose value of X axis was the number of cases carrying this mutation out of 47 Chinese AHC cases, and value of Y axis was the number of carriers out of 106 European/American AHC cases. The background showed the P-value of Fisher's exact test and dashed line represented 0.05 significant level. (B) Overall population difference of ATP1A3 according to F_st values. The dots and solid line represented F_st values of informative SNPs in the populations of Chinese, European and American, and the dotted line represented all eleven populations in HapMap Project. The threshold of F_st were set according to S. Wright [40].