Table 3.
Tumor Genotypes
| Mutation Status | Placebo Arm (n = 258) |
Imatinib Arm (n = 249) |
All Patients (n = 507) |
|||
|---|---|---|---|---|---|---|
| No. | % | No. | % | No. | % | |
| KIT exon 9 | 22 | 8.5 | 13 | 5.2 | 35 | 6.9 |
| KIT exon 11 | 171 | 66.3 | 170 | 68.3 | 341 | 67.3 |
| Any deletion | 92 | 35.7 | 92 | 37.0 | 184 | 36.3 |
| Deletion of codons 557 and/or 558 | 56 | 21.7 | 51 | 20.5 | 107 | 21.1 |
| Deletion not including codon 557 or 558 | 36 | 14.0 | 41 | 16.5 | 77 | 15.2 |
| Insertion | 25 | 9.7 | 21 | 8.4 | 46 | 9.1 |
| Point mutation | 54 | 20.9 | 57 | 22.9 | 111 | 21.9 |
| KIT exon 13 | 6 | 2.3 | 3 | 1.2 | 9 | 1.8 |
| KIT exon 17 | 0 | 0.0 | 1 | 0.4 | 1 | 0.2 |
| PDGFRA | 27 | 10.5 | 30 | 12.0 | 56 | 11.2 |
| D842V | 12 | 4.6 | 15 | 6.0 | 27 | 5.3 |
| Not D842V | 15 | 5.8 | 15 | 6.0 | 30 | 5.9 |
| WT | 32 | 12.4 | 32 | 12.8 | 64 | 12.6 |
Abbreviation: WT, wild type.