Table 5.
Characteristics of Hodgkin lymphoma patients according to IDO expression
| Variable | IDO high | IDO low |
|---|---|---|
| Sex |
Male |
Female |
| Age group |
Older |
Young |
| Histologic type |
MC, LD, LR |
NLP, NS |
| Ann Arbor stages |
Advanced stage |
Limited stage |
| IPS |
High |
Low |
| B symptom |
Present |
Absent |
| EBV or HIV infection |
positive |
Not accompanied |
| FOXP3/CD4* | High | Low |
*FoxP3/CD4 significantly correlated with IDO in cases with limited stages.
IDO, indoleamine 2,3-dioxygenase; MC, mixed cellularity; LD, lymphocyte-depleted; LR, lymphocyte-rich; NLP, nodular lymphocyte predominant; NS, nodular sclerosis; IPS, international prognostic score.