Table 3.
Correlations between cytokines expressed in cutaneous and mucosal lesions detected as protein and mRNA a
| |
CL
b
|
ML
c
|
||||
|---|---|---|---|---|---|---|
| Correlations | n | r | p | n | r | p |
| IL-32 x TNF |
21 |
-0.15 |
0.51 |
9 |
0.88 |
0.003* |
| IL-32 x IL-10 |
22 |
-0.03 |
0.90 |
8 |
0.11 |
0.79 |
| TNF x IL-10 |
20 |
0.38 |
0.10 |
8 |
0.38 |
0.36 |
| mRNA IL-32 vs. mRNA TNF |
8 |
-0.17 |
0.70 |
7 |
-0.21 |
0.66 |
| mRNA IL-32 vs. mRNA IL-10 |
8 |
-0.17 |
0.70 |
7 |
0.18 |
0.71 |
| mRNA TNF vs. mRNA IL-10 | 10 | 0.28 | 0.43 | 6 | 0.65 | 0.18 |
aIL-32, TNF and IL-10 proteins were detected by IHC and IL-32γ, TNF and IL-10 mRNA were detected by qPCR, in biopsy fragments of lesions from bCutaneous leishmaniasis (CL) and cMucosal leishmaniasis (ML) patients. n = number of samples; r = Spearman´s correlation test. *p < 0.05.