Table 1.

Mapping efficiencies and CpG coverage of libraries created with different insert sizes: 50–150, 150–250, and 250–350 bp.

Insert size (bp)	% Mapping	Total no. CpGs	CpGs with ≥ 10x coverage
50–150	38.3	2,094,731	1,067,789
150–250	61.4	3,264,576	1,711,904
250–350	61.7	2,104,633	1,346,714

For reference, the whole genome is estimated to contain ~28,000,000 CpG sites.