Table 2.
MDDR1 structure activity classes
| Activity index | Activity class | Active molecules | Pair-wise similarity |
|---|---|---|---|
| 07707 |
Adenosine (A1) agonists |
207 |
0.424 |
| 07708 |
Adenosine (A2) agonists |
156 |
0.484 |
| 31420 |
Renin inhibitors 1 |
1300 |
0.584 |
| 42710 |
CCK agonists |
111 |
0.596 |
| 64100 |
Monocyclic -lactams |
1346 |
0.512 |
| 64200 |
Cephalosporins |
113 |
0.503 |
| 64220 |
Carbacephems |
1051 |
0.414 |
| 64500 |
Carbapenems |
126 |
0.444 |
| 64350 |
Tribactams |
388 |
0.673 |
| 75755 | Vitamin D analogous | 455 | 0.569 |