Table 4.
MUV structure activity classes
| Activity index | Activity class | Pair-wise similarity |
|---|---|---|
| 466 |
S1P1 rec. (agonists) |
0.445 |
| 548 |
PKA (inhibitors) |
0.430 |
| 600 |
SF1 (inhibitors) |
0.445 |
| 644 |
Rho-Kinase2 (inhibitors) |
0.416 |
| 652 |
HIV RT-RNase (inhibitors) |
0.398 |
| 689 |
Eph rec. A4 (inhibitors) |
0.449 |
| 692 |
SF1 (agonists) |
0.365 |
| 712 |
HSP 90 (inhibitors) 30 |
0.413 |
| 713 |
ER-a-Coact. Bind. (inhibitors) |
0.389 |
| 733 |
ER-b-Coact. Bind. (inhibitors) |
0.352 |
| 737 |
ER-a-Coact. Bind. (potentiators) |
0.502 |
| 810 |
FAK (inhibitors) |
0.425 |
| 832 |
Cathepsin G (inhibitors) |
0.435 |
| 846 |
FXIa (inhibitors) |
0.532 |
| 852 |
FXIIa (inhibitors) |
0.492 |
| 858 |
D1 rec. (allosteric modulators) |
0.400 |
| 859 | M1 rec. (allosteric inhibitors) | 0.386 |