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High GE-based risk score is associated with a shorter time to the first treatment in CLL patients. The prognostic value of GE-based risk score was tested in two independent cohorts of CLL patients. A high GE-based risk score is associated with a shorter time to the first treatment in the two independent cohorts ((a) n = 70, P = 7.9E − 9 and (b) n = 130, P = 0.01) and in patients with cytogenetically defined good prognostic ((c) n = 52, P = 1E − 5).
