Table 4. Summary of relations among fluorophores, cellular or metabolic functions, and expected versus measured fluorescence signals and lifetimes at emission wavelengths.
Biochemical fluorophores in prostate tissue | Relations to cellular/metabolic functions of tissue |
Fluorescence expected (spectral band; peaks)
in nm [ 28 ] |
Fluorescence measured
[see Fig. 4(a) ] (τ: lifetime in ns) |
||
---|---|---|---|---|---|
Peak | τ; cancer | τ; benign | |||
Porphyrins | Tissue vasculature | > 600; 630, 680 | 632 nm 684 nm |
2.59 ± 0.49 2.17 ± 0.40 |
2.22 ± 0.45 1.85 ± 0.32 |
Flavins | cellular metabolism | 500-600; 550 | 532 nm 562 nm |
3.12 ± 0.44 3.03 ± 0.48 |
2.72 ± 0.37 2.63 ± 0.38 |
Lipopigments | cellular disposal process | 450-670; 560 | 532 nm 562 nm 632 nm |
3.12 ± 0.44 3.03 ± 0.48 2.59 ± 0.49 |
2.72 ± 0.37 2.63 ± 0.38 2.22 ± 0.45 |