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. 2014 May 5;2014:438070. doi: 10.1155/2014/438070

Figure 2.

Figure 2

Bronchoalveolar lavage fluid fractions of FoxP3+ CD4+ T cells, Th17, and IFN-γ +Th17 in sarcoidosis, other DPLDs, and healthy control subjects. (a) Lower fractions of regulatory T cells, defined as FoxP3+ CD4+ T cells, in sarcoidosis compared to other DPLDs and HC. (b) Lower Th17 cell fractions of CD4+ T cells in sarcoidosis compared to HC (median: 2.5% versus 4.5%, P = 0.011). (c) Higher IFN-γ + fraction of Th17 cells in sarcoidosis compared to HC (median: 72.4% versus 31%, P = 0.0005). Pairwise comparisons were done with Mann-Whitney U test. DPLD: Diffuse parenchymal lung disease; HC: healthy controls.