Table 1.
Basic characteristics of the study population.
| Characteristic | Sarcoidosis (N = 30) |
Other DPLDs (N = 18) |
Healthy controls (N = 15) |
P* |
|---|---|---|---|---|
| Age, years (range) | 46 (37–56)## | 63 (48–72)§§ | 35 (30–49) | 0.03 |
|
| ||||
| Sex (male/female) | 23/7 | 11/7 | 8/7 | 0.25 |
|
| ||||
| Smokers (current/former/never) | 1/9/20 | 4/7/7 | 0/3/12 | 0.03** |
|
| ||||
| FEV1, percentage of predicted | 80 (68–90) | 75 (63–88)§§ | 101 (95–104) | <0.001 |
|
| ||||
| FEV1/FVC | 0.78 (0.73–0.83)# | 0.82 (0.78–0.88) | 0.85 (0.81–0.86) | 0.03 |
|
| ||||
| TLCO, percentage of predicted | 92 (77–102)## | 57 (53–69)§§ | 103 (98–109) | 0.01 |
Data are shown as median (IQR) unless otherwise stated. *P values represent pairwise comparison between Sarcoidosis and healthy controls with Mann-Whitney U test conducted if significant differences were found with Kruskal-Wallis test. §§ P < 0.01 compared to healthy controls. # P < 0.05 and ## P < 0.01 compared to other DPLD. **P value from chi-squared test. DPLD: diffuse parenchymal lung disease; FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity; TLCO: transfer factor of the lung for carbon monoxide.