Fig. 7.

Mutations in PV 2C^ATPase known to affect encapsidation or uncoating. The genomic structure of PV is shown at the top of the figure. The locations of the pseudo-revertant and suppressor variants of mutants CRS2 and CRS4 and of previously published 2C^ATPase mutant variants 11b (Wang et al., 2012), 2C-31 R1 and 2C-31 R3 (Li & Baltimore, 1990) are indicated. The temperatures at which the transfection (Tf) and first passage (P1) and the plaque purifications were carried out are listed on the right.