Table 5.
Hypersusceptibility of NNRTIr HIV to AZT-triazole NRTIs
| Compound | EC50 WT HIV (μM) | EC50 NNRTIr HIV (μM) | ratio NNRTIr/WT |
|---|---|---|---|
| 9d | >5.0 | 2.4 | < 0.5 |
| 17d | 7.2 | 2.1 | 0.3 |
| 17f | 4.7 | 1.0 | 0.2 |
| 18a | 1.0 | 0.6 | 0.6 |
| 18e | 4.1 | 1.8 | 0.4 |
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