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. 2012 Dec 2;4(1):113–117. doi: 10.1021/ml300335r

Table 4. Rat PK Profile of Compound 19.

route Clc (mL/min/kg) Vd (L/kg) t1/2e (h) AUCf (h ng/mL) % Fg
iva 36 2.0 0.7 460  
pob     3.2 18200 88
a

1 mg/kg.

b

50 mg/kg.

c

Clearance.

d

Volume of distribution.

e

Half-life.

f

Area under the curve.

g

Oral bioavailability.