Table 2. Mouse PK Parameters of Selected Compounds Following Single Oral Dosinga.
ID | dose (mg/kg) | AUClast (μg·h/mL) | Cmax (μg/mL) | t1/2 (h) |
---|---|---|---|---|
2d | 50 | 64.9 | 19.6 | 2.4 |
2g | 50 | 251.2 | 15.5 | 8.8 |
2i | 50 | 136.5 | 12.0 | 2.3 |
2j | 50 | 8.3 | 2.3 | 4.7 |
Suspension formulation: 1% Klucel LF in water with 0.1% Tween 80.