Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Monoubiquitination of FANCI has no impact on DNA binding. (A) FANCI monoubiquitination (20-h incubation) was conducted with oligonucleotide O1 (64 nucleotides) as DNA co-factor. A control reaction without DNA (lane 1) was performed. (B) After affinity purification (left and middle panels), the unmodified FANCI and the monoubiquitinated preparation were tested for DNA binding using linear dsDNA and splayed-arm DNA (right panel), as in Figure 4.
