Enzymatic degradation
of indolicidin and ld-indolicidin.
(A–D) HPLC chromatograms of indolicidin andld-indolicidin
after 0, 5, 10, 30, 60, and 120 min of tryptic or α-chymotryptic
degradation. (E,F) Covalent structure of peptide fragments and (G,H)
percentage of indolicidin (△) and ld-indolicidin (▲)
in the PBS buffer solution containing trypsin or α-chymotrypsin
at 37 °C at different time points. (I) Amino acid sequences of
the peptides and enzymes used in the present study.