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. 2013 Sep 22;4(11):1074–1078. doi: 10.1021/ml400280z

Table 4. In Vitro Antibacterial Activity of Compounds 2023 Bearing a [1,2,3]Triazole C-5 Side Chain on the Oxazolidinone Ring.

  minimum inhibitory concentration (μg/mL)
compd S.a.a S.a.b S.a.c S.a.d E.f.e E.f.f M.c.g S.p.h S.p.i H.i.j
1 2 2 2 32 4 2 8 1 0.5 16
20 0.25 0.5 0.25 4 0.5 0. 5 4 ≤0.063 ≤0.063 4
21 0.125 0.25 0.125 2 0.25 0.25 2 ≤0.063 ≤0.063 2
22 0.25 0.5 0.25 8 0.5 0.25 8 ≤0.063 ≤0.063 4
23 0.125 0.25 0.25 2 0.25 0.25 4 ≤0.063 ≤0.063 2
a

Staphylococcus aureus SR20549.

b

Staphylococcus aureus Smith.

c

Staphylococcus aureus SR3637 (methicillin-resistant).

d

Staphylococcus aureus NRS271(linezolid-resistant).

e

Enterococcus faecalis SR1004.

f

Enterococcus faecium SR7940 (vancomycin-resistant).

g

Moraxella catarrhalis SR26840.

h

Streptococcus pneumonoiae SR26207.

i

Streptococcus pneumonoiae SR11031 (penicillin-resistant).

j

Haemophilus influenzae SR27914.