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. 2013 Jul 3;4(8):800–805. doi: 10.1021/ml400197u

Figure 3.

Figure 3

Relationship between lipophilicity (logD), human plasma protein binding (log Ki), and microsomal stability (CLint) and the N7 substituent in a series of matched molecular pairs. Markers are colored by the C5 substituent and arranged vertically according to N7 group.