Table 4. Fraction Unbound (fu) in Rat and Human Plasma and log D7.4 for Compounds 1, 2, and 7.
| fu % (rat) | fu % (human) | log D7.4 | |
|---|---|---|---|
| 1 | 4.4 | 4.7 | 3.1 |
| 2 | 7.2 | 6.7 | 3.2 |
| 7 | 2.9 | 2.7 | 4.0 |
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