Table 1. In Vitro Growth Inhibitory Activities against Various Cancer Cell Lines.
cancer type | cell line | characteristic | 9n (μM) | 9p (μM) | gefitinib (μM) |
---|---|---|---|---|---|
epidemal | A431 | EGFRWT,overexpression | 2.2 | 0.9 | 4.0 |
NSCLC | H1975 | EGFRL858R/T790M | 4.9 | 3.61 | 10.48 |
NSCLC | A549 | EGFRWT,κ-Ras mutation | >10 | >10 | >10 |
colon | SW620 | EGFR negative | 25.4 | 6.2 | 28.20 |
malignant myeloid | K562 | EGFR negative | >10 | >10 | >10 |