Table 1. Solubility of SPD304 in 10 mM Citrate-Phosphate Buffer (pH 6.5) Containing Various Concentrations of Different Organic Solvents^a.

solubility of SPD304 (μM)
solvent/concn	2.5% (v/v)	5% (v/v)	10% (v/v)
DMSO	33	52	79
DMF	35	58	82
glycerol	15	19	28
MeOH	37	58	83
PEG3350	71	84	96
PEG5000	90	97	>100

^aThe solubility of SPD 304 in 0% solvent is 10 μM. The mean values of four independent measurements are presented.