Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Reagents and conditions: (a) Na2CO3, MeCN, 25 °C. (b) Fe, NH4Cl, EtOH/H2O, 70 °C. (c) Isopropylisothiocyanate, pyridine, 70 °C, then EDC. (d) sec-BuLi, THF, −78 °C, then ClCO2Et. (e) KOH, THF/EtOH/H2O, 70 °C. (f) Me2NH, T3P, (iPr)2NEt, DCM, 0 °C. (g) 1 N HCl, DCM, 25 °C. (h) Aryl bromide, Pd(OAc)2, (ortho-biphenyl)(tBu)2P, Cs2CO3, 1,4-dioxane, 100 °C.
