Table 3. MIC for 13 in E. coli Efflux Mutant Parent and LigA Target Mutant Strains.
| MIC (μg/mL) | |
|---|---|
| E. coli | compd 13 |
| TOP10 ΔTolC | 8 |
| TOP10 ΔTolC LigA G180E | 128/64 |
| TOP10 ΔTolC LigA R150S | 128/64 |
| TOP10 ΔTolC LigA R518H | 64 |
| E. coli LigA IC50 (uM) | 0.097 |
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