Table 1. In Vivo Antimalarial Activity of Compounds 19–34 against Multidrug-Resistant P. yoelii nigeriensis in Swiss Mice by oral and im Routes.

^aPercent suppression = [(c – t)/c] × 100, where c = parasitaemia in control group, and t = parasitaemia in treated group.

^b100% suppression of parasitaemia means that the number of parasites, if present, is below the detection limit.