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. 2014 Jan 22;5(4):422–427. doi: 10.1021/ml500002n

Figure 2.

Figure 2

Effect of C7 substitution on serum shift for compounds with substructure 25. (A) Box plot (N = 47 compounds) showing difference in serum shift for compounds with or without R7 substituents. (B) Scatter plot of ssEC50 vs EC50 (nM) for the same 47 compounds). Determined using recombinant NL4.3 virus (T124A IN mutant).