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. 2014 Feb 8;5(4):416–421. doi: 10.1021/ml4005232

Table 3. Potency and Onset Time of β2-Adrenoceptor Agonism in Isolated Tissuea.

compd guinea pig onset time (min) human onset time (min) cLogP type
AZD3199 22 11 6.0 dibasic
1 90 n/d 4.5 monobasic
7 6 n/d 3.7 dibasic
14 13 n/d 4.9 dibasic
16 11 n/d 5.5 dibasic
sibenadet 58 n/d 2.5 monobasic
indacaterol 77 49 3.0 monobasic
formoterol 23 13 1.3 monobasic
salmeterol 90 t/s 3.1 monobasic
salbutamol 3 19 0.1 monobasic
a

n/d = not determined; t/s = onset time too slow to measure.