Figure 2.

K-26 binding in both domains of ACE. (A) K-26 (green) bound in the N-domain of ACE. (B) K-26 (cyan) bound in the C-domain of ACE. Residues involved in K-26 interactions are shown as gray sticks. The zinc ion is shown as an orange sphere and water molecules in red. Potential hydrogen interactions and water mediated ones are presented with black and red dashed lines, respectively. Omit maps for K-26 bound to the N- and C-domains are shown at the 1σ contour level.