Table 2. Inhibition of Overexpressed Bacterial Dicarboxypeptidases by K-26.
dicarboxypeptidase | type | captopril IC50 (M) | K-26 IC50 (M) |
---|---|---|---|
somatic ACE | M3 | 7.7 × 10–9 | 2.5 × 10–8 |
K26DCP | M2 | 5.2 × 10–9 | 4 × 10–5 |
EcDCP | M2 | 1.6 × 10–8 | 1.5 × 10–4 |
MR1DCP | M3 | 9.2 × 10–9 | 1.1 × 10–5 |