Table 2.
Neuropsychological data in patients with MSA-C and control subjects
| Test | MSA-C (n = 26) | Controls (n = 26) | p-value |
|---|---|---|---|
| Attention | |||
| Digit span (forward, 9) | 6.9 (1.5) | 6.7 (1.3) | NS |
| Digit span (backward, 8) | 4.0 (1.6) | 4.8 (1.7) | 0.09 |
| Digit span total (17) | 10.9 (2.6) | 11.5 (2.8) | NS |
| Language and related function | |||
| K-BNT (60) | 52.2 (5.5) | 51.3 (6.0) | NS |
| Repetition (15) | 14.7 (0.6) | 15.0 (0.2) | 0.01 |
| Calculation (12) | 11.3 (1.1) | 11.4 (1.1) | NS |
| Visuospatial function | |||
| RCFT (36) | 30.6 (7.0) | 35.4 (0.9) | 0.001 |
| Verbal memory function | |||
| 3 words registration (3) | 3.0 (0.2) | 3.0 (0.0) | NS |
| 3 words recall (3) | 1.8 (2.0) | 2.7 (0.5) | <0.0001 |
| SVLT | |||
| Immediate recall (36) | 18.9 (4.5) | 23.7 (4.0) | <0.0001 |
| Delayed recall (12) | 5.2 (2.6) | 8.4 (1.7) | <0.0001 |
| Recognition (24) | 20.5 (2.4) | 22.3 (1.3) | 0.002 |
| Visual memory function (RCFT) | |||
| Immediate recall (36) | 17.0 (9.4) | 21.3 (5.1) | 0.05 |
| Delayed recall (36) | 16.4 (8.9) | 21.1 (4.7) | 0.02 |
| Recognition (24) | 18.8 (2.2) | 19.7 (1.2) | 0.09 |
| Frontal executive function | |||
| Contrasting program (20) | 20.3 (1.8) | 19.9 (0.5) | NS |
| Go-no-go test (20) | 19.6 (3.3) | 19.9 (0.4) | NS |
| COWAT (Animal) | 13.9 (3.6) | 17.0 (3.4) | 0.002 |
| COWAT (Supermarket) | 15.6 (4.2) | 20.5 (4.0) | <0.001 |
| Phonemic generative naming | 25.4 (7.3) | 30.9 (8.0) | 0.01 |
| Word stroop test (112) | 104.0 (20.9) | 111.6 (1.4) | 0.07 |
| Color stroop test (112) | 82.5 (23.7) | 93.0 (15.7) | 0.07 |
MSA-C: multiple system atrophy if cerebellar features are predominant, K-BNT: the Korean version of Boston Naming Test, RCFT: rey complex figure test, SVLT: seoul verbal learning test, COWAT: the controlled oral word association Test. Values are expressed as mean (standard deviation), NS: not significant. Number in parenthesis of test column indicates possible maximal performance score