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Daidzein analogs enhance osteogenesis of MSCs as early as Day 7. MSCs from three donors were induced to undergo osteogenic differentiation and simultaneously exposed to vehicle (DMSO), estrogen (10 nM), or daidzein analogs (1 μM) at every medium change for 7 days. The mean bone differentiation potential of the three donors is shown. *, P < 0.05; #, P < 0.01.
