. 2014 Feb 4;5(4):428–433. doi: 10.1021/ml500005m

Table 6. Effect of 29 on the Extracellular Glycine Levels in Rat Striatum at 10 mg/kg po^a and Its Plasma and Brain Exposures.

max. fold incr. of glycine	fold incr. of glycine at 3 h	plasma^b (ng/mL)	brain^b (ng/mL)	brain^b GlyT1 EC₅₀
1.7	1.5	713	60	13

n = 6.

Measured at 3 h postdosing.

Table 6. Effect of 29 on the Extracellular Glycine Levels in Rat Striatum at 10 mg/kg poa and Its Plasma and Brain Exposures.