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. Author manuscript; available in PMC: 2014 May 20.
Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Sep 15;907:117–125. doi: 10.1016/j.jchromb.2012.09.018

Table 5.

Precision (RSD) and accuracy (RE) of spiked samples (n = 5) with 1500.0 ng/mL analyte concentration in plasma and brain homogenate diluted 15 folds into ULOQ (100 ng/mL) concentration.

Plasma Brain

Analyte Nominal Conc. (ng/mL) Measured Conc. (ng/mL) RSD (%) RE (%) Measured Conc. (ng/mL) RSD (%) RE (%)

COT 1500.0 1420.92±29.02 2.04 −5.27 1530.24±26.03 1.70 2.02
NCOT 1362.81±30.01 2.20 −9.15 1613.43±15.44 0.96 7.56
OHCOT 1370.49±36.11 2.63 −8.63 1656.96±30.67 1.85 10.46
COTNO 1275.69±30.65 2.40 −14.95 1583.43±23.89 1.51 5.56