Figure 2.
Elevated expression of the hepatic Mogat1 in mouse models of disease. (a) Significant elevation of the hepatic Mogat1 expression accompanied with the progression of diabetes in KKAy mice. Data are shown as relative expression levels against 4w of control mice. (b,c) Higher expression of the hepatic Mogat1 in (b) db/db and (c) DIO mice. The expression of Mogat1 mRNA in liver was analyzed by quantitative reverse transcription PCR (n = 4–5). Mean ± SD are shown for all panels. *P < 0.05, **P < 0.01, Student's t-test. DIO, diet-induced obesity; Mogat1, monoacylglycerol O-acyltransferase 1.