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. Author manuscript; available in PMC: 2014 Jun 25.
Published in final edited form as: Biochemistry. 2013 Jun 14;52(25):4364–4372. doi: 10.1021/bi400342t

Figure 5. Mitochondrial function is decreased in response to combination of NO and quinone.

Figure 5

BAEC were exposed to Deta/NO (500 µM) for 1 h prior to treatment with menadione (20 µM, white bars) or DMNQ (20 µM, grey bars) for an additional 4 h. Black bars represent control treatment. (A) Basal oxygen consumption rate (OCR), (B) ATP-linked OCR and (C) reserve capacity OCR were measured using extracellular flux technology. OCRs were normalized to total protein per well after completion of assay. Values represent means ± SE; n = 3 to 4. * p < 0.05 compared to control, ** p < 0.05 compared to samples without Deta/NO.