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MGE-cell transplants reverse the enhanced locomotor activity observed in MAM-treated rats with low and high dose (0.5, 2.0 mg/kg) amphetamine (n=12-17 rats per group; *#represents a mean effect of treatment; Three-way ANOVA). Inset demonstrates that MGE transplants produce the opposite response (i.e. augment the locomotor activity) to low-dose amphetamine in control, saline-treated rats.
