Table 4. Effect of IgY against diarrhea in Mice.
| Study | No. of mortality by diarrhea (or) No. with diarrhea/No. in Group (%) | Outcome measure considered - Mortality (M) or Diarrhea (D) | Relative Risk (RR) | 95% Confidence Interval (CI) | |
| Intervention | Control | ||||
| Animal Class: Mice | |||||
| Bacterial Pathogen | |||||
| Peralta 1994 | 6/27 (22) | 17/25 (68) | M | 0.327 | 0.154 to 0.695 |
| Yokoyama 1998 | 3/15 (20) | 12/15 (80) | M | 0.250 | 0.0881 to 0.710 |
| 6/10 (60) | 10/10 (100) | M | 0.600 | 0.362 to 0.995 | |
| Jacoby 2001 | 2/10 (20) | 4/10 (40) | D | 0.500 | 0.117 to 2.139 |
| Wang 2010 | 0/12 (0) | 12/12 (100) | M | 0.040 | 0.00265 to 0.605 |
| Neri 2011 | 0/6 (0) | 5/6 (83) | M | 0.091 | 0.00621 to 1.330 |
| Parma 2011 | 0/4 (0) | 4/4 (100) | M | 0.111 | 0.00814 to 1.516 |
| Feng 2013 | 0/5 (0) | 4/5 (80) | M | 0.111 | 0.00768 to 1.608 |
| Viral Pathogen | |||||
| Bartz 1980 | 3/20 (15) | 30/33 (91) | D | 0.165 | 0.0578 to 0.471 |
| Hatta 1993 | 0/16(0) | 14/16(83) | D | 0.035 | 0.00224 to 0.532 |
| 4/12 (37) | 12/12 (100) | D | 0.333 | 0.150 to 0.742 | |
| Kuroki 1993 | 1/12 (8.33) | 11/12 (91) | D | 0.091 | 0.0138 to 0.598 |
| 2/12 (16.6) | 11/12 (91) | D | 0.182 | 0.0507 to 0.652 | |
| Sarker 2007 | 1/15 (6) | 10/15 (67) | D | 0.100 | 0.0146 to 0.687 |
| Ngyuen 2010 | 0/6 (0) | 6/6 (100) | M | 0.077 | 0.00536 to 1.103 |
| Liou 2010 | 0/21 (0) | 21/23 (91) | M | 0.026 | 0.00164 to 0.395 |
| 5/25 (20) | 16/26 (62) | M | 0.325 | 0.140 to 0.753 | |
| 5/16 (31) | 17/22 (77) | M | 0.404 | 0.189 to 0.866 | |
| 1/19 (5) | 6/19 (32) | M | 0.167 | 0.0221 to 1.255 | |
| 2/19 (11) | 4/19 (21) | M | 0.500 | 0.104 to 2.412 | |
| Buragohain 2012 | 7/21 (33) | 23/23 (100) | D | 0.333 | 0.182 to 0.610 |
| 0/19 (0) | 9/18 (50) | D | 0.050 | 0.00312 to 0.798 | |
| Pooled random effects | 0.250 | 0.175 to 0.358 | |||
Test for Heterogeneity: Q = 36.17; DF = 21; P = 0.0209, I2 = 41.94% (95% CI for I2 = 3.60 to 65.03).