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. 2014 May 20;9(5):e97716. doi: 10.1371/journal.pone.0097716

Table 7. Prophylactic effect of IgY against diarrhea in Piglets.

Study No. of mortality by diarrhea (or) No. with diarrhea/No. in Group (%) Outcome measure considered - Mortality (M) or Diarrhea (D) Relative Risk (RR) 95% Confidence Interval (CI)
Intervention Control
Animal Class: Pig
Bacterial Pathogen
Imberechts 1997 2/6 (33) 4/6 (66) D 0.500 0.141 to 1.772
2/8 (25) 6/8 (75) D 0.333 0.0941 to 1.181
0/8 (0) 2/8 (25) M 0.200 0.0112 to 3.576
Marquardt 1999 1/8(12.5) 5/8(26.5) M 0.200 0.0296 to 1.351
0/10(0) 3/10 (30) M 0.143 0.00837 to 2.438
Owsu-Asiedu 2002 7/24(30) 13/18 (73) D 0.404 0.203 to 0.802
8/24(33) 18/18 (100) D 0.333 0.189 to 0.587
Owsu-Asiedu 2003a 1/15(6.6) 6/15 (40) M 0.167 0.0227 to 1.222
Owsu-Asiedu 2003b 0/18 (0) 8/24(33) M 0.078 0.00480 to 1.265
Chernysheva 2004 8/12 (66) 8/12 (66) D 1.000 0.568 to 1.761
Chu 2006 1/6 (16.7) 4/6 (66.7) M 0.250 0.0383 to 1.633
Li 2009 0/4(0) 3/4 (75) D 0.143 0.01000 to 2.041
Sarandan 2010 0/3 (0) 3/3 (100) D 0.143 0.0110 to 1.860
Viral Pathogen
Kweon 2000 5/19 (26) 10/17(58) M 0.447 0.191 to 1.048
Zuo 2009 1/8 (12.5) 4/7 (57) M 0.219 0.0314 to 1.526
Vega 2012 0/4(0) 6/6(100) D 0.111 0.00814 to 1.516
Pooled random effects 0.381 0.265 to 0.549

Test for Heterogeneity: Q = 19.39; DF = 15; P = 0.1965, I2 = 22.65% (95% CI for I2 = 0.00 to 57.44).