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. 2014 May 20;9(5):e97422. doi: 10.1371/journal.pone.0097422

Figure 1. sP-selectin, sE-selectin and cytokine/chemokine plasma levels in ApoE−/− HFD mice receiving daily injections of recombinant sP-selectin or sE-selectin.

Figure 1

A) Plasma levels of sP-selectin after 8 or 16 weeks of daily s.c injections (22.5 µg/kg/day) of vehicle control (saline matched volume; white bar), sP-selectin (black bar) or sE-selectin (checkered bar). B) Plasma levels of sE-selectin after 8 or 16 weeks of daily s.c injections (22.5 µg/kg/day) of vehicle control (saline matched volume; white bar), sP-selectin (black bar) or sE-selectin (checkered bar). C) Plasma levels of IL-1β, MCP-1, MIP-1α and RANTES after 8 or 16 weeks of daily s.c injections (22.5 µg/kg/day) of vehicle control (saline matched volume; white bar), sP-selectin (black bar) or sE-selectin (checkered bar). n = 9–15 mice per treatment group. Data represented as Mean (ng or pg/ml) ± SEM where *, ** and ** represents P<0.05, <0.01 and <0.001 respectively (from saline treatment) as analysed by One-way ANOVA with Tukey’s post-hoc test.