Figure 4. Plasma cytokine and chemokine levels after sP-selectin treatment for 16weeks in SM22α-hDTR ApoE^−/− HFD.

Plasma levels of MCP-1, MIP-1α and RANTES after 8 or 16 weeks of daily s.c injections (22.5 µg/kg/day) of vehicle control (saline matched volume; white bar), sP-selectin (black bar) or sE-selectin (checkered bar). n = 9–15 mice per treatment group. Data represented as Mean (pg/ml) ± SEM where * represents P<0.05 (from saline treatment) as analysed by unpaired students t-test.