Skip to main content
. Author manuscript; available in PMC: 2014 May 20.
Published in final edited form as: J Exp Zool B Mol Dev Evol. 2010 Dec 6;0(2):113–134. doi: 10.1002/jez.b.21383

Figure 8.

Figure 8

Transcriptional profiles of hormone-related genes. We analyzed expression profiles of groups of genes related to hormonal signaling pathways. (A) The majority of hormone-related transcripts follow a pattern of increased expression during larval and metamorphic stages. Several representatives are plotted here: Cerebrin (DA37072), thyroid hormone induced protein (DA7089), thyroid hormone sulfotransferase (DA47476), Aplysia bag cell peptide (BCP–DA16715), Thyrostimulin subunit (GPHB5–DA37011), and corticotrophin-releasing hormone binding protein (CRF-BP–DA42138). (B) We analyzed the expression of insulin-like peptides and insulin-like growth factors separately. Relative expression patterns of selected examples are: Insulin-like peptide (DA42444), Insulin-like growth factor binding protein 3 (IGFBP-3–DA36214), and Insulin-like growth factor binding protein 7 (IGFBP-7–DA20244). The cytochrome P-450 (CYP) family is a large group of enzymes with functions related to steroid, drug, carcinogen, and mutagen metabolism. From 40 transcripts coding for CYP, we were able to identify 3 that are differentially up-regulated during metamorphic competence only (C). Many hormones signal through nuclear hormone receptors. We annotated seven new NHRs from the A. californica transcriptome and plotted three of them in (D).