Table 1.Ulk1/2 DKO pups show high perinatal mortality.
Offspring from Ulk1+/−ulk2−/− parents | ||||
---|---|---|---|---|
Genotype | Total | Observed (%) | Expected (%) | |
ED18.5 | 1+/+2−/− | 38 | 27.7 | 25.0 |
1+/−2−/− | 71 | 51.8 | 50.0 | |
1−/−2−/− | 28 | 20.4 | 25.0 | |
P1 | 1+/+2−/− | 56 (2 dead day 1) | 35.6 | 25.0 |
1+/−2−/− | 80 (3 dead day 1) | 50.0 | 50.0 | |
1−/−2−/− | 23 (21 dead day 1) | 14.4 | 25.0 |
All pups in consecutive litters from 16 breeding pairs were included in the analysis for the mice at P1.