Figure 3. Sensitivity assessment.
Clinician UPDRS – Part 3 score for finger tapping (A), Clinician MBRS ratings of finger tapping speed (B), Clinician ratings of MBRS finger tapping amplitude (C), Kinesia ratings of finger tapping speed (D), and, Kinesia ratings of finger tapping amplitude (E). Scores are plotted for a single subject with DBS turned off (0V) and voltage amplitude gradually increased to its established optimal setting during the three repetitions of the finger tapping task. The x's, +'s, and O's correspond to scores from the first, second, and third repetitions of ratings. The gray shading on each plot indicates voltage amplitudes that result in scores significantly different from baseline at the alpha = 0.05 significance level using Tukey's HSD (“honestly significant difference”) test.