Figure 2.
Influence of oral treatment of lethally-irradiated mouse recipients on engraftment of mouse BM cells in a short-term non-competitive assay. One hundred thousand B6.BoyJ (CD45.1+) donor cells were injected i.v. into C57Bl/6 (CD45.2+) recipient mice 24 hours after 950cGy radiation. The recipient mice were treated 4 hours after radiation with either oral administered control diluent or 200 μg sitagliptin. Results are shown as mean percent engraftment ±1SEM for 5 mice/group at one month post donor BM cell infusion with all mice surviving. a, significantly different from control treated recipients, p<0.001.
