Figure 1.

The effect of a brief period of cortical deactivation by muscimol-infused Elvax pledgets. A, Extracellular recordings from cortical region AES immediately after implanting the pledget and before its muscimol had an effect on neuronal activity (top), after its effect was evident as the suppression of neuronal activity (middle), and after depletion of the muscimol stores and the return of neuronal activity (bottom). All recordings were taken from the same electrode in an adult control animal. B, The accuracy with which the adult localized visual (circles) and spatiotemporally concordant visual–auditory (squares) stimuli before Elvax implantation (left), after implantation and during its effective period (middle), and after muscimol depletion (right). Multisensory and unisensory response accuracies were rendered equivalent (middle) during the period in which the muscimol was effective.