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. 2014 Mar 6;35(20):1335–1344. doi: 10.1093/eurheartj/ehu081

Table 2.

C-statistics (%) with and without QTcFram interval

Women, age (years)
Men, age (years)
Model 50–70 (n = 63 475) 70–90 (n = 35 650) 50–70 (n = 56 589) 70–90 (n = 17 815)
CVD Model without QTcFram 73.0 70.4 69.9 66.8
Model with QTcFram 73.1 70.6 70.6 67.7
Difference +0.1 +0.2 +0.7 +0.9
Non-CVD Model without QTcFram 70.1 64.8 67.2 63.0
Model with QTcFram 70.0 64.8 67.6 62.9
Difference −0.1 +0.0 +0.3 −0.1

C-statistics was based on internal cross validation using 100 bootstrap samples without replacement. Predictions were based on Cox models fitted within the respective age- and gender-determined subgroups and were adjusted for covariates as described in Figure 2.