Table 2.
Women, age (years) |
Men, age (years) |
||||
---|---|---|---|---|---|
Model | 50–70 (n = 63 475) | 70–90 (n = 35 650) | 50–70 (n = 56 589) | 70–90 (n = 17 815) | |
CVD | Model without QTcFram | 73.0 | 70.4 | 69.9 | 66.8 |
Model with QTcFram | 73.1 | 70.6 | 70.6 | 67.7 | |
Difference | +0.1 | +0.2 | +0.7 | +0.9 | |
Non-CVD | Model without QTcFram | 70.1 | 64.8 | 67.2 | 63.0 |
Model with QTcFram | 70.0 | 64.8 | 67.6 | 62.9 | |
Difference | −0.1 | +0.0 | +0.3 | −0.1 |
C-statistics was based on internal cross validation using 100 bootstrap samples without replacement. Predictions were based on Cox models fitted within the respective age- and gender-determined subgroups and were adjusted for covariates as described in Figure 2.