Fig. 3.
Stride length, gait width and intrastep distance is altered in SYN-OE mice with advancing age. A) Stride length is decreased in SYN-OE mice evaluated at 12 months of age, but is unaltered in wildtype (WT) mice. No difference in stride length in SYN-OE mice is observed at 4 or 6 months of age compared to WT. B) Gait width is increased in SYN-OE mice at 12 months of age. No difference in gait in SYN-OE mice is observed at 4 or 6 months of age compared to WT. C) Intrastep distance is decreased in SYN-OE mice evaluated at 12 months of age, but is unaltered in WT mice. No difference in gait width in SYN-OE mice is observed at 4 or 6 months of age compared to WT. *, p ≤ 0.01 relative to WT at 12 months.