Figure 1).

Linear mixed-model predictions for the models describing provincial antimicrobial prescriptions per 1000 inhabitant-days (PrIDs) (A) and defined daily doses (DDDs) per prescription (B) dispensed by outpatient pharmacies in Canada (2000 to 2010). Data for the provinces of Prince Edward Island (PEI) and Newfoundland and Labrador were provided as combined values for 2000 to 2004. As of 2005, the data were provided at the individual provincial level. To ensure model conversion, the analysis had to be performed with Newfoundland and Labrador and PEI separately, including the years from 2000 to 2004. This was possible by assigning the same data values to both provinces during this time period